Home › Words › U › unfatigueunfatigueunfatigue means to free from fatigue.Among words judged in Lexicurio's Arena, unfatigue ranks #3,411 of 42,747 for Qualifying.EtymologyFrom un- + fatigue.verbTo free from fatigue.e.g.“[…] a work, like the present, calculated to unfatigue the mind and delight the imagination […]” — 1882, William Shakespeare, William Harness, The Complete Works of William Shakespeare, page 230:Definitions & examples from Wiktionary (CC BY-SA 3.0).