ultrasupernatantEtymologyFrom ultra- + supernatant.nounThe supernatant produced by ultracentrifugation“This fraction should be much “cleaner” than exosomal RNA preps isolated using commercial exosome isolation kits; in particular, the P3 pellet should be relatively free of cell debris and microvesicles (which are likely to be removed in the P1 and P2 fractions, respectively) and soluble protein complexes (which are likely to remain in the ultrasupernatant).”