Home › Words › S › superfemalesuperfemalesuperfemale means A female with an additional X chromosome in each cell (triple X syndrome).Among words judged in Lexicurio's Arena, superfemale ranks #13,407 of 42,747 for Qualifying.EtymologyFrom super- + female.nounA female with an additional X chromosome in each cell (triple X syndrome).Definitions & examples from Wiktionary (CC BY-SA 3.0).