Home › Words › M › megalopolizemegalopolizemegalopolize means to turn into a megalopolis.Among words judged in Lexicurio's Arena, megalopolize ranks #31,664 of 42,752 for Qualifying.EtymologyFrom megalopolis + -ize.verbTo turn into a megalopolis.Definitions & examples from Wiktionary (CC BY-SA 3.0).