macrodose/ˈmækɹoʊˌdoʊs/EtymologyFrom macro- + dose; contrast microdose.nounA relatively large dose of (something, such as a drug or radiation), particularly as contrasted with a microdose.“Here macrodose is defined as the average dose for a large-size object such as a liver or a tumour.”verbTo take a relatively large dose of (something, particularly a drug), particularly as contrasted with microdosing.“Much less expensive than either is macrodosing with vitamins C, D, and E, which has been shown to be beneficial in slowing the progression of osteoarthritis of the knee.”