holdase

Etymology

From hold + -ase?

holdase means A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them. Lexicurio rates it Rare gem — a strength score of 82 out of 100.

noun

A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them.“As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients.”