Home › Words › H › histotopehistotopehistotope · noun — the portion of an antigen that reacts with or binds to a T-cell.Definition from Wiktionary (CC BY-SA 3.0).Among words judged in Lexicurio's Arena, histotope ranks #26,454 of 43,053 for Qualifying.EtymologyFrom histo- + -tope.nounThe portion of an antigen that reacts with or binds to a T-cell.e.g.“Thus, a mutation affecting the structure of a class II molecule changes the co-recognition specificity of a histotope on the APC of the mutant.” — 1984, William E. Paul, Immunogenetics, page 156:Definitions & examples from Wiktionary (CC BY-SA 3.0).Words closest in meaningBy meaning, not spelling — each word's AI semantic fingerprint, nearest first.desetope 60% match — The part of an MHC that binds to an antigen. vs histotope →paratope 58% match — That part of the molecule of an antibody that binds to an antigen. vs histotope →agretope 53% match — The part of a biomolecule that binds to the major histocompatibility complex molecule vs histotope →histotyping 52% match — The analysis of histotypes, such as in diagnosis and prognosis. vs histotope →aptatope 51% match — The binding-site of an aptamer vs histotope →epitope 51% match — The part of a biomolecule (such as a protein) which is the target of an immune response vs histotope →apotope 51% match — an immunogenic epitope expressed on apoptotic cells vs histotope →immunoepitope 50% match — Synonym of epitope. vs histotope →