bolus/ˈbəʊləs/EtymologyFrom Late Latin bōlus (“clod of earth, lump”), plural bōlī, from Ancient Greek βῶλος (bôlos, “clod, lump”). Doublet of bole.bolus means A round mass of something, especially of chewed food in the mouth or alimentary canal. Lexicurio rates it Rare gem — a strength score of 79 out of 100.nounA round mass of something, especially of chewed food in the mouth or alimentary canal.A single, large dose of a drug, especially one in that form.“I gave him a bolus, twice the size of a gooseberry.”verbTo administer (a drug) in bolus dosing, that is, dosing in (one or more) boluses.To take a bolus (dose) of insulin at a mealtime in order to control one's blood glucose level in diabetes.