acetaminophen/əˌsitəˈmɪnəfən/EtymologyShortening of the chemical name para-acetylaminophenol. By surface analysis, acet- + amino- + -phen.acetaminophen means A white crystalline compound used in medicine as an anodyne to relieve pain and reduce fever. Lexicurio rates it Rare gem — a strength score of 71 out of 100.nounA white crystalline compound used in medicine as an anodyne to relieve pain and reduce fever.“You need to take acetaminophen / Or just a little aspirin / acetylsalicylic for the pain”